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Structure of 77326-62-6
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2-Amino-6-bromobenzonitrile features a bromine atom at the para position relative to the nitrile group, enabling facile cross-coupling reactions. The amino functionality provides a handle for derivatization, while the electron-withdrawing nitrile enhances reactivity in palladium-catalyzed transformations. This compound serves as a key intermediate in the synthesis of bioactive heterocycles and functionalized aromatic systems.
2-Amino-6-bromobenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other nitrogen-containing heterocycles via standard coupling and cyclization protocols. The molecule exhibits excellent bench stability, tolerates a range of reaction conditions, and facilitates straightforward purification due to its crystalline nature. Its dual functionality—amine and nitrile—supports orthogonal derivatization strategies, making it a reliable scaffold for targeted molecular design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: