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Structure of 78449-73-7
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(Hexahydro-1H-pyrrolizin-7a-yl)methanamine features a saturated pyrrolizidine core with a primary amine at the 7a-position, offering high nucleophilicity and solubility in polar solvents. This bench-stable, moisture-tolerant scaffold integrates readily into bioactive molecules and serves as a key building block for medicinal chemistry applications.
(Hexahydro-1H-pyrrolizin-7a-yl)methanamine serves as a versatile nitrogen-containing building block for the synthesis of biologically active heterocycles. Its saturated pyrrolizidine core offers enhanced metabolic stability and favorable pharmacokinetic properties, while the primary amine functionality enables straightforward derivatization via acylation, alkylation, or coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic protocols, facilitating efficient access to complex scaffolds in medicinal chemistry and process development.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: