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Structure of 870708-39-7
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1-(2-Chlorophenyl)cyclopropan-1-amine features a rigid cyclopropane ring fused to an electron-deficient 2-chlorophenyl group, delivering enhanced metabolic stability. This structural motif enables direct incorporation into bioactive scaffolds, particularly in CNS-targeted pharmaceuticals and kinase inhibitors. The molecule exhibits favorable lipophilicity and planar geometry, facilitating membrane permeability and target engagement.
1-(2-Chlorophenyl)cyclopropan-1-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmacologically relevant scaffolds. Its cyclopropyl amine moiety exhibits favorable metabolic stability and enhances target binding through conformational constraint. The ortho-chlorophenyl group provides a handle for further functionalization via palladium-catalyzed cross-coupling reactions. This compound demonstrates robust bench stability and compatibility with standard purification techniques, facilitating its use in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: