Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-Methyl-1-(o-tolyl)methanamine

  • CAS No. 874-33-9

  • Cat. No. CS-0045339
  • Molecule weight135.21
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Methyl-1-(o-tolyl)methanamine|CS-0045339

Structure of 874-33-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 874-33-9
  • Cat. No. CS-0045339
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃N
  • Molecular Weight 135.21
  • Synonym(s) N-methyl(2-methylphenyl)methanaminium
  • SMILES CC1=CC=CC=C1CNC

Description

N-Methyl-1-(o-tolyl)methanamine is a bench-stable, moisture-tolerant amine featuring a methylated nitrogen adjacent to a benzene ring substituted with a methyl group at the ortho position. This structure imparts enhanced electron density and steric bulk, enabling efficient coupling in pharmaceutical synthesis and facilitating selective functionalization in complex molecular scaffolds.

Application

N-Methyl-1-(o-tolyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive amine scaffolds through standard functional group transformations. Its ortho-substituted aromatic core provides steric and electronic modulation, while the tertiary amine functionality offers favorable solubility and metabolic stability. The compound exhibits bench stability and compatibility with common coupling and reduction protocols, facilitating efficient synthesis of target molecules in drug discovery workflows.

Synthesis

  • Route1
    • In-stock
      2-Methylbenzaldehyde|CS-W008902
      529-20-4
    • null|null
      74-89-5
    • ~96%
    • In-stock
      N-Methyl-1-(o-tolyl)methanamine|CS-0045339
      874-33-9

    References

    • Warner-Lambert Company LLC Patent: US2006/111422 A1, 2006 ; Location in patent: Page/Page column 53 ; US 20060111422 A1
  • Route2
    • null|null
      18100-53-3
    • ~97%
    • In-stock
      N-Methyl-1-(o-tolyl)methanamine|CS-0045339
      874-33-9

    References

    • Piazzi, Lorna; Belluti, Federica; Bisi, Alessandra; Gobbi, Silvia; Rizzo, Stefano; Bartolini, Manuela; Andrisano, Vincenza; Recanatini, Maurizio; Rampa, Angela Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 575 - 585
  • Route3

    References

    • Organic Letters, , vol. 13, # 4 p. 600 - 603

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.71442
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • N-Methyl-1-(o-tolyl)methanamine sigmaN-Methyl-1-(o-tolyl)methanamine manufacturerN-Methyl-1-(o-tolyl)methanamine priceN-Methyl-1-(o-tolyl)methanamine structureN-Methyl-1-(o-tolyl)methanamine SDSbuy N-Methyl-1-(o-tolyl)methanamineN-Methyl-1-(o-tolyl)methanamine supplierN-Methyl-1-(o-tolyl)methanamine usesN-Methyl-1-(o-tolyl)methanamine molecular weightprice of N-Methyl-1-(o-tolyl)methanamineN-Methyl-1-(o-tolyl)methanamine chemical name formula of N-Methyl-1-(o-tolyl)methanamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label