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Structure of 875306-20-0
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2-Bromo-6-iodo-4-(trifluoromethyl)aniline features a trifluoromethyl group that imparts high electron-withdrawal and metabolic stability, while the bromo and iodo substituents enable selective cross-coupling reactions. This ortho-heteroaryl scaffold supports efficient diversification in medicinal chemistry and materials synthesis under standard conditions.
2-Bromo-6-iodo-4-(trifluoromethyl)aniline serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling the construction of complex biaryl scaffolds. The ortho-bromo and meta-iodo substituents offer complementary reactivity in Suzuki, Stille, and Negishi couplings, while the trifluoromethyl group enhances metabolic stability and lipophilicity. Its bench-stable crystalline form facilitates handling and purification, making it suitable for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: