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Structure of 87864-14-0
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A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS, in which the biotin is separated from the lysine side-chain by a 6 C-atom spacer. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSBiotinylation Reagents for Peptide Synthesis
2-Chloro-N-(2-(diethylamino)ethyl)quinoline-4-carboxamide serves as a versatile building block in medicinal chemistry, enabling the construction of quinoline-based scaffolds through palladium-catalyzed coupling reactions. The chloro group at the 2-position facilitates nucleophilic substitution, while the carboxamide functionality supports hydrogen bonding and solubility optimization. Its diethylaminoethyl side chain enhances solubility and provides a handle for further derivatization. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: