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Structure of 889944-74-5
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6-Chloro-2-methylpyridine-3-sulfonyl chloride features a sulfonyl chloride group flanked by electron-withdrawing chlorine and methyl substituents, enabling selective acylation in heterocyclic synthesis. This bench-stable reagent integrates efficiently into pharmaceutical intermediates and functionalized materials, offering high reactivity under mild conditions with minimal side reactions.
6-Chloro-2-methylpyridine-3-sulfonyl chloride serves as a versatile sulfonyl chloride building block for the synthesis of sulfonamide-containing compounds. Its reactivity enables efficient coupling with amines under mild conditions, facilitating rapid access to functionalized pyridine derivatives. The chloro and methyl substituents provide orthogonal handles for further derivatization, while the sulfonyl chloride group offers excellent bench stability and ease of purification, making it well-suited for high-throughput medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: