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Structure of 908247-29-0
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4-(Cyclopropylethynyl)benzoic acid features a rigid, electron-deficient aryl ring paired with a sterically constrained cyclopropylethynyl group, enabling selective coupling in late-stage functionalization. This robust scaffold integrates readily into bioactive architectures under standard conditions, offering enhanced metabolic stability and favorable pharmacokinetic properties.
4-(Cyclopropylethynyl)benzoic acid serves as a versatile building block for the synthesis of functionalized aromatic systems, enabling efficient Sonogashira coupling reactions under standard conditions. The terminal alkyne moiety exhibits high stability and compatibility with diverse functional groups, facilitating downstream derivatization in medicinal chemistry and materials science. Its carboxylic acid handle allows direct incorporation into amides, esters, or heterocyclic scaffolds, supporting rapid access to bioactive compounds and conjugated architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: