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(R)-Methyl 5-amino-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate

  • CAS No. 929039-92-9

  • Cat. No. CS-M0513
  • Purity≥95%
  • MDL No.MFCD18642695

*For research and further manufacturing use only, not for direct human use.

(R)-Methyl 5-amino-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate|CS-M0513

Structure of 929039-92-9

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General Information

  • CAS No. 929039-92-9
  • Cat. No. CS-M0513
  • Purity ≥95%
  • MDL No. MFCD18642695
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₄F₃NO₃S
  • Molecular Weight 345.34
  • Synonym(s) GSK-461364A intermediate
  • SMILES O=C(OC)C1=C(O[C@H](C)C2=C(C=CC=C2)C(F)(F)F)C=C(N)S1

Synthesis

  • Route1
    • (R)-Methyl 5-nitro-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate|CS-M0512
      929039-94-1
    • ~92%
    • (R)-Methyl 5-amino-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate|CS-M0513
      929039-92-9

    References

    • Kuntz, Kevin; Emmitte, Kyle Allen; Rheault, Tara Renae; Smith, Stephon; Hornberger, Keith; Dickson, Hamilton; Cheung, Mui Patent: US2008/300247 A1, 2008 ; Location in patent: Page/Page column 53-54 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.55
  • LogP   4.2757
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   4

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