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Structure of 935777-24-5
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6-(Trifluoromethyl)pyridazin-3-amine features a trifluoromethyl group that imparts strong electron-withdrawing character and enhanced metabolic stability. This nitrogen-rich heterocycle integrates readily into medicinal chemistry scaffolds, offering improved solubility and binding affinity in target-directed drug discovery programs.
6-(Trifluoromethyl)pyridazin-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the pyridazinamine core offers reliable reactivity in amide bond formation, Suzuki-Miyaura coupling, and electrophilic functionalization. Bench-stable and readily purified, it functions as a key intermediate in the synthesis of kinase inhibitors and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: