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Structure of 944401-58-5
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This boronate-functionalized pyrimidine amine features a stable tetramethylboronate group enabling efficient Suzuki-Miyaura coupling under mild conditions. The electron-deficient pyrimidine core pairs with the trifluoromethyl substituent to enhance reactivity and metabolic stability, making it ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. Its trifluoromethylpyrimidine core enables efficient construction of biologically relevant heterocyclic scaffolds, while the stable tetramethylboronate group facilitates mild reaction conditions, excellent functional group tolerance, and straightforward purification. This reagent is well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: