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Structure of 1249610-72-7
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2-Chloro-4-(methoxymethyl)pyridine features a pyridine core functionalized with a chlorine atom at the 2-position and a methoxymethyl group at the 4-position, delivering enhanced reactivity and solubility. This combination enables efficient incorporation into pharmaceutical intermediates and agrochemical scaffolds, where its electron-deficient ring facilitates nucleophilic substitution. The methoxymethyl moiety offers stability under standard conditions while permitting controlled deprotection in late-stage synthesis.
2-Chloro-4-(methoxymethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via cross-coupling and nucleophilic substitution reactions. The chloropyridine moiety provides high reactivity under palladium-catalyzed conditions, while the methoxymethyl group offers orthogonal handle for selective derivatization. Bench-stable and compatible with standard purification protocols, it facilitates the synthesis of complex heterocyclic scaffolds and API intermediates with predictable regioselectivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: