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Structure of 1445-39-2
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2-Amino-5-iodopyrimidine is a bench-stable heterocyclic building block featuring a reactive iodine atom at the 5-position and an amino group at the 2-position. This combination enables direct coupling in palladium-catalyzed cross-coupling reactions, facilitating rapid access to functionalized pyrimidine derivatives for medicinal chemistry and materials science applications.
2-Amino-5-iodopyrimidine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biologically relevant pyrimidine scaffolds. The iodine substituent facilitates reliable C–C and C–N bond formation under standard conditions, while the amino group offers direct functionalization potential. This compound exhibits good bench stability and is compatible with diverse reaction environments, making it ideal for the synthesis of kinase inhibitors and other heterocyclic drug candidates.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: