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Structure of 167073-08-7
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This fluorinated cyclopropane carboxylic acid features a strained three-membered ring with a stereo-defined fluorine substituent, delivering enhanced metabolic stability and conformational rigidity. The (1R,2S) configuration enables precise spatial orientation in bioactive molecules, making it valuable for medicinal chemistry applications requiring defined geometry.
(1R,2S)-2-Fluorocyclopropane-1-carboxylic acid serves as a conformationally constrained building block in medicinal chemistry, enabling the study of stereocontrolled bioactive molecule synthesis. Its fluorinated cyclopropane core imparts metabolic stability and modulates electronic properties, while the carboxylic acid functionality facilitates direct derivatization via amide formation, esterification, or coupling reactions. Bench-stable and readily purified by recrystallization, it functions reliably in standard peptide coupling and heterocycle construction workflows.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H228
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Precautionary Statements : P210-P240-P241-P280-P370+P378
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Lot numbers can be found on the outside label of a product: