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Structure of 173943-98-1
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Spiro[isochroman-1,4'-piperidine] hydrochloride features a rigid spirocyclic architecture that enhances metabolic stability and modulates lipophilicity. This scaffold integrates a nitrogen-rich piperidine ring with an isochroman core, delivering favorable solubility and bioavailability. The hydrochloride salt form improves crystallinity and handling under standard bench conditions.
Spiro[isochroman-1,4'-piperidine] hydrochloride serves as a versatile scaffold for medicinal chemistry campaigns, offering a rigid spirocyclic architecture that enhances metabolic stability and target selectivity. The piperidine nitrogen provides a basic site for salt formation and derivatization, while the isochroman moiety enables π-stacking interactions in biological targets. This compound demonstrates bench stability, compatibility with standard coupling reactions, and ease of purification—making it a practical building block for exploratory synthesis of CNS-targeted molecules and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: