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Structure of 174566-15-5
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2,4-Dichloro-7-fluoroquinazoline serves as a pivotal building block in the synthesis of kinase inhibitors and bioactive heterocycles. The molecule features a fluorinated quinazoline core with strategically positioned chlorine substituents that enhance electrophilicity and facilitate downstream coupling reactions under standard conditions. This configuration enables efficient integration into pharmaceutical scaffolds requiring electron-deficient aromatic systems.
2,4-Dichloro-7-fluoroquinazoline serves as a versatile building block for the synthesis of kinase inhibitors and other bioactive heterocycles. Its reactivity profile enables selective nucleophilic substitution at C-2 or C-4, facilitating rapid diversification through coupling with amines, thiols, and other nucleophiles. The molecule exhibits excellent bench stability and ease of purification, making it well-suited for scalable medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: