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Structure of 185220-68-2
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2-Chloro-6-iodopyridin-3-ol features a halogenated pyridine core with complementary reactivity at the 2-chloro and 6-iodo positions, enabling selective cross-coupling transformations. The phenolic hydroxyl group enhances solubility and serves as a handle for derivatization. This bench-stable compound facilitates efficient access to complex heterocyclic architectures in medicinal chemistry and materials synthesis.
2-Chloro-6-iodopyridin-3-ol serves as a versatile building block in the synthesis of functionalized pyridine derivatives. Its orthogonal halogenation pattern enables sequential cross-coupling reactions, with the chlorine facilitating Suzuki-Miyaura coupling and the iodine supporting Stille or Negishi protocols. The phenolic hydroxyl group provides a handle for derivatization or protection, enhancing synthetic flexibility. Bench-stable and amenable to standard purification methods, it supports efficient construction of complex heterocyclic scaffolds relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: