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Structure of 22235-25-2
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Methyl 3-amino-5-(trifluoromethyl)benzoate features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability, while the amino functionality enables direct derivatization. This scaffold integrates readily into pharmaceutical intermediates and functional materials under standard conditions.
Methyl 3-amino-5-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry, enabling direct incorporation of electron-withdrawing trifluoromethyl and amino functionalities into heterocyclic scaffolds. Its stability under standard synthetic conditions facilitates nucleophilic substitution, palladium-catalyzed coupling, and electrophilic functionalization. The methyl ester group offers convenient derivatization potential, while the ortho-amino and para-trifluoromethyl substituents provide complementary reactivity for sequential transformations in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: