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CS-W001157 4
Total: USD 88.00

(R)-3-N-Boc-3-(Methylamino)piperidine

  • CAS No. 309962-67-2

  • Cat. No. CS-B0443
  • Purity≥95%
  • MDL No.MFCD09878596

*For research and further manufacturing use only, not for direct human use.

(R)-3-N-Boc-3-(Methylamino)piperidine|CS-B0443

Structure of 309962-67-2

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General Information

  • CAS No. 309962-67-2
  • Cat. No. CS-B0443
  • Purity ≥95%
  • MDL No. MFCD09878596
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂N₂O₂
  • Molecular Weight 214.30
  • Synonym(s) tert-butyl N-methyl-N-[(3R)-3-piperidyl]carbamate
  • SMILES O=C(OC(C)(C)C)N(C)[C@H]1CNCCC1

Description

(R)-3-N-Boc-3-(Methylamino)piperidine features a chiral piperidine core with a Boc-protected amine and a methylamino substituent, enabling direct incorporation into asymmetric synthesis. The protected nitrogen facilitates selective functionalization while maintaining stereochemical integrity under standard conditions.

Application

(R)-3-N-Boc-3-(methylamino)piperidine serves as a versatile chiral building block for medicinal chemistry, enabling efficient access to piperidine-based scaffolds prevalent in bioactive molecules. The Boc-protected amine offers excellent bench stability and orthogonal functionality, facilitating selective deprotection and downstream derivatization. Its defined stereochemistry supports consistent biological activity in target-directed synthesis.

Synthesis

  • Route1
    • null|null
      1124199-23-0
    • ~97%
    • In-stock
      (R)-3-N-Boc-3-(Methylamino)piperidine|CS-B0443
      309962-67-2

    References

    • US2009/62252 A1, ; Page/Page column 44 ; US 20090062252 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.6053
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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