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Structure of 312736-49-5
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3,5-Dichloropyrazine-2-carboxylic acid features a pyrazine core bearing two chlorine substituents at the 3 and 5 positions and a carboxylic acid group at the 2 position. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and tunable polarity for drug discovery applications.
3,5-Dichloropyrazine-2-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to pyrazine-based scaffolds. Its dichloro substitution pattern facilitates directed metalation and subsequent functionalization, while the carboxylic acid group supports straightforward derivatization via amide, ester, or amidation reactions. The compound exhibits good bench stability and is compatible with standard coupling protocols, making it well-suited for parallel library synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: