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CS-W001157 4
Total: USD 88.00

5,6-Dihydro-2H-pyran-2-one

  • CAS No. 3393-45-1

  • Cat. No. CS-0037765
  • Purity≥96%
  • MDL No.MFCD00010439

*For research and further manufacturing use only, not for direct human use.

5,6-Dihydro-2H-pyran-2-one|CS-0037765

Structure of 3393-45-1

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General Information

  • CAS No. 3393-45-1
  • Cat. No. CS-0037765
  • Purity ≥96%
  • MDL No. MFCD00010439
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆O₂
  • Molecular Weight 98.10
  • Synonym(s) None
  • SMILES O=C1OCCC=C1

Description

Enantioselective conjugate addition of Grignard reagents to 5,6-dihydro-2H-pyran-2-one catalyzed by a chiral phosphine-copper iodide catalyst has been reported.5,6-Dihydro-2H-pyran-2-one has been used in the preparation of:(1aR,5aR,5bS,6S,7S)-6,7-di-tert-butoxy-5-oxo-pyrrolidino[1,2-b]isoxazolidino[4,5-c]tetrahydropyran4-(phenyl)tetrahydro-2H-pyran-2-one

Synthesis

  • Route1
    • null|null
      3174-74-1
    • ~72%
    • In-stock
      5,6-Dihydro-2H-pyran-2-one|CS-0037765
      3393-45-1

    References

    • Bonadies, Francesco; Fabio, Romano Di; Bonini, Carlo Journal of Organic Chemistry, 1984 , vol. 49, p. 1647 - 1649
  • Route2
    • null|null
      71309-70-1
    • ~68%
    • In-stock
      5,6-Dihydro-2H-pyran-2-one|CS-0037765
      3393-45-1

    References

    • Minami, Ichiro; Takahashi, Kazuhiko; Shimizu, Isao; Kimura, Tsuneo; Tsuji, Jiro Tetrahedron, 1986 , vol. 42, # 11 p. 2971 - 2978
  • Route3
    • null|null
      100591-69-3
    • ~86%
    • In-stock
      5,6-Dihydro-2H-pyran-2-one|CS-0037765
      3393-45-1

    References

    • Pohmakotr, Manat; Jarupan, Prapanpong Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2253 - 2256

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Warning
UN#: 1224
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.4895
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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