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Structure of 343781-53-3
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3,6-Dichloropicolinaldehyde features a highly electrophilic aldehyde group flanked by two chlorine substituents at the 3- and 6-positions of the pyridine ring. This electron-deficient heterocycle enables efficient coupling in nucleophilic addition reactions, particularly in the synthesis of functionalized imines and heterocyclic scaffolds under mild conditions. The molecule exhibits excellent bench stability and solubility in common organic solvents, facilitating straightforward handling in process development workflows.
3,6-Dichloropicolinaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of substituted heterocycles and functionalized aromatic systems. Its ortho-dichloro substitution pattern enhances electrophilic reactivity while maintaining bench stability. The aldehyde group facilitates condensation reactions, including imine formation and Mannich-type cyclizations, with high functional group tolerance and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: