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Structure of 4361-44-8
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3-Cyclohexylpropan-1-amine features a linear aliphatic chain terminating in a primary amine, flanked by a cyclohexyl group that imparts significant hydrophobic character and conformational rigidity. This structure supports its use in ligand design and as a building block for bioactive molecules requiring enhanced membrane permeability and metabolic stability.
3-Cyclohexylpropan-1-amine serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of bioactive scaffolds through amine-mediated coupling reactions. Its aliphatic amine functionality exhibits excellent reactivity in amide bond formation and conjugate addition processes, while the cyclohexyl ring imparts favorable lipophilic character and conformational rigidity. The compound demonstrates good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and intermediate development in API discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: