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Structure of 49674-16-0
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5-Amino-3-bromobenzonitrile features a bromine substituent at the meta position relative to the nitrile group, enabling selective coupling reactions. The amino functionality enhances solubility and reactivity in cross-coupling processes. This electron-rich scaffold serves as a key intermediate for pharmaceutical and agrochemical synthesis.
5-Amino-3-bromobenzonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal functional groups. The amino and nitrile moieties provide sites for derivatization, while the bromine facilitates Suzuki, Stille, or Negishi couplings. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for multi-step synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312+H332-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: