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Structure of 53135-45-8
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4-Methoxy-2-methylpyrimidin-5-amine features a pyrimidine core bearing a methoxy group at C4 and a methyl substituent at C2, enhancing solubility and metabolic stability. The aniline-like amine at C5 enables facile coupling reactions in medicinal chemistry. This scaffold integrates readily into kinase inhibitors and antiviral agents due to its favorable electronic profile and planar geometry.
4-Methoxy-2-methylpyrimidin-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. Its ortho-substituted structure supports regioselective functionalization and exhibits favorable bench stability, facilitating straightforward purification and integration into standard coupling reactions. The molecule functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive heterocycles, leveraging its dual electron-donating groups for enhanced reactivity in cross-coupling and cyclization protocols.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: