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Structure of 791626-58-9
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6-Bromoquinolin-2-amine features a bromine substituent at the 6-position of a quinoline scaffold bearing a strategically placed amino group at the 2-position. This combination enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive heterocycles. The molecule exhibits enhanced solubility in organic solvents and stability under standard bench conditions, making it suitable for synthetic workflows in medicinal chemistry and materials science.
6-Bromoquinolin-2-amine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling direct functionalization at the C6 position via palladium-catalyzed cross-coupling reactions. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the amino group offers orthogonality for selective derivatization. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it ideal for constructing quinoline-based scaffolds in API development and probe synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: