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Structure of 190273-89-3
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6-Bromoquinazolin-2-amine is a bench-stable heterocyclic building block featuring a bromine atom at the 6-position and an amino group at the 2-position. This combination enables direct functionalization in cross-coupling reactions, facilitating rapid access to diverse quinazoline-based scaffolds for medicinal chemistry and materials science applications.
6-Bromoquinazolin-2-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position via palladium-catalyzed cross-coupling reactions. Its bromine substituent exhibits excellent compatibility with Suzuki, Stille, and Negishi couplings, facilitating rapid diversification of quinazoline scaffolds. The molecule demonstrates bench stability, ease of purification, and tolerance to common functional groups, making it well-suited for iterative synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: