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Structure of 886373-70-2
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5-Chloro-2-methoxypyridin-3-amine features a pyridine core bearing chloro and methoxy substituents at electron-deficient positions, enabling selective coupling in cross-coupling reactions. The amine group provides a reactive handle for derivatization, while the methoxy moiety enhances solubility and modulates electronic properties. This compound serves as a key intermediate in pharmaceutical synthesis and functional material design.
5-Chloro-2-methoxypyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through palladium-catalyzed cross-coupling reactions. Its chloro group facilitates C–C and C–N bond formation under standard conditions, while the methoxy and amino functionalities provide orthogonal reactivity for further functionalization. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthesis workflows in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: