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Structure of 1363381-22-9
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tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate is a sterically shielded spirocyclic lactam precursor featuring a bench-stable ketone at the C7 position and a protected carboxylic acid ester at C2. This scaffold integrates seamlessly into complex nitrogen-containing heterocycles, enabling efficient access to bioactive alkaloid frameworks through mild deprotection and functionalization.
tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic building block for the synthesis of nitrogen-containing heterocycles, particularly in medicinal chemistry and natural product derivatization. The molecule combines a stable tert-butyl ester with a ketone at C7 and a secondary amine at C2, enabling selective functionalization via reductive amination, enolate chemistry, or nucleophilic addition. Its rigid spiro scaffold enhances conformational control, while the bench-stable nature and straightforward purification support scalable applications in multi-step synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: