Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 4-amino-3-(trifluoromethyl)benzoate

  • CAS No. 167760-75-0

  • Cat. No. CS-W006108
  • Molecule weight219.16
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 4-amino-3-(trifluoromethyl)benzoate|CS-W006108

Structure of 167760-75-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 167760-75-0
  • Cat. No. CS-W006108
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈F₃NO₂
  • Molecular Weight 219.16
  • Synonym(s) benzoic acid, 4-amino-3-(trifluoromethyl)-, methyl ester
  • SMILES O=C(OC)C1=CC=C(N)C(C(F)(F)F)=C1

Description

Methyl 4-amino-3-(trifluoromethyl)benzoate features a trifluoromethyl group enhancing electron-withdrawal and metabolic stability, paired with a primary amine enabling facile derivatization. This aromatic ester integrates readily into synthetic routes for pharmaceutical intermediates, offering improved solubility and bench-stable handling under standard conditions.

Application

Methyl 4-amino-3-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and API intermediates. The ortho-trifluoromethyl group enhances metabolic stability, while the amino and ester functionalities provide orthogonal handles for derivatization via coupling, acylation, or cyclization reactions. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows requiring high functional group tolerance and predictable reactivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.32
  • LogP   2.0742
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 167760-75-0 sigma167760-75-0 manufacturer167760-75-0 price167760-75-0 structure167760-75-0 SDSbuy 167760-75-0167760-75-0 supplier167760-75-0 uses167760-75-0 molecular weightprice of 167760-75-0167760-75-0 chemical name formula of 167760-75-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label