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Structure of 173435-32-0
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2-Fluoro-4-methylpyridin-3-amine features a strategically positioned fluorine atom and methyl group on the pyridine ring, delivering enhanced electron density at the nitrogen site. This configuration enables efficient coupling reactions in medicinal chemistry, particularly in constructing kinase inhibitors and bioactive heterocycles under standard conditions.
2-Fluoro-4-methylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds through palladium-catalyzed cross-coupling reactions. Its fluorine and amino groups provide orthogonal reactivity for late-stage functionalization, while the methyl group enhances metabolic stability. The compound exhibits good bench stability, facilitates straightforward purification, and functions effectively in standard coupling protocols, making it a practical choice for API development and synthetic route optimization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: