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Structure of 52764-11-1
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2,6-Dichloro-3-hydroxypyridine features a pyridine core functionalized with two chlorine atoms at the 2 and 6 positions and a hydroxyl group at the 3 position. This electron-deficient heterocycle serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, offering enhanced reactivity in nucleophilic substitution processes. The ortho-chlorine arrangement provides steric protection to the hydroxyl group, improving stability under standard handling conditions.
2,6-Dichloro-3-hydroxypyridine serves as a versatile building block for functionalized pyridine scaffolds, enabling direct substitution at the C3 position via nucleophilic displacement or metal-catalyzed coupling. The hydroxyl group provides a handle for derivatization, while the ortho-dichloro substitution pattern ensures high reactivity and regioselective transformation under mild conditions. Its bench-stable nature and compatibility with common protecting group strategies make it ideal for iterative synthesis in medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: